- General Drug Summary
- Description
- A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
- Also Known As
- Acedapsone; DADPS; Dapson; Dapsonum; DDS; Dds, Diaphenylsulfone; Dds, Pharmaceutical; Diamino-diphenyl sulphone; Diaminodifenilsulfona; Diaminodiphenyl Sulfone; Diaphenylsulfon; Diaphenylsulfone; Diaphenylsulphon; Diaphenylsulphone; Diphenasone; Metabolite C; N, N'-Diphenyl Sulfondiamide; P-Aminophenyl Sulfone; P, P'-Sulfonyldianiline; P,P-Diaminodiphenyl Sulphone; P,P-Sulfonylbisbenzamine; P,P-Sulfonylbisbenzenamine; P,P-Sulphonylbisbenzamine; P,P-Sulphonylbisbenzenamine; P,P-Sulphonyldianiline; P,P'-Diaminodiphenyl Sulfone; Sulfonyldianiline; Sulphadione; Sulphonyldianiline
- Categories
- Antimycobacterials
- Structure
- Summary In Neonatal Jaundice
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1 record(s) for Dapsone Adverse Event in Neonatal Jaundice.
- PMID
- Drug Name
- Efficacy
- Evidence
- 2717998
- Dapsone
- Adverse Event
- Case Report
- Summary
- the first case of Neonatal hyperbilirubinemia after maternal dapsone therapy for leprosy.
- Neonatal hyperbilirubinemia after treatment of maternal leprosy. Southern medical journal, 1989 May [Go to PubMed]
- Leprosy occurs rarely in women of reproductive age. Until this report, the treatment of leprosy with dapsone has not been associated with any adverse fetal or neonatal side effects. We have reported what we believe to be the first case of neonatal hyperbilirubinemia after maternal dapsone therapy for leprosy.