- General Drug Summary
- Description
- A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]
- Also Known As
- Folate; Pteroyl-L-glutamic acid; Pteroyl-L-monoglutamic acid; Pteroylglutamic acid; Pteroylmonoglutamic acid; Vitamin B9; Vitamin Bc; Vitamin Be; Vitamin M
- Groups
- approved; nutraceutical
- Structure
- Summary In Neonatal Jaundice
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1 record(s) for Folic Acid Chemoprevention in Neonatal Jaundice.
- PMID
- Drug Name
- Efficacy
- Evidence
- 7293869
- Folic Acid
- Chemoprevention
- Clinical Trial
- Summary
- On these basis of prophylaxis has been attempted by treating newborns with folic acid, alpha-tocopherol and vitamins B1, B2, B6 and C.
- [Vitamin prophylaxis for immature infant anemia (author's transl)]. Acta vitaminologica et enzymologica, 1980 [Go to PubMed]
- The cause of the Premature Infant Anemia (PIA) is mainly an insufficient erythropoiesis, a shorter mean-life of the red cells and in increased hemolysis. On these basis of prophylaxis has been attempted by treating newborns with folic acid, alpha-tocopherol and vitamins B1, B2, B6 and C. 208 premature babies have been treated (birth weight higher than 1750 nr. 171; birth weight less than 1750 nr. 37). Several parameters have been evaluated: weight gain, erythrocyte and reticulocyte count, jaundice occurrence and number of transfusions needed. The results on the blood parameters was good for the small babies group and sufficient for the others. Differences have been observed between the two groups for the occurrence of jaundice and transfusions.
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1 record(s) for Folic Acid Effective in Maintaining Remission in Neonatal Jaundice.
- PMID
- Drug Name
- Efficacy
- Evidence
- 3223347
- Folic Acid
- Effective in Maintaining Remission
- Case Report
- Summary
- Play a maintenance role in this report.
- Neonatal hyperbilirubinemia caused by pyruvate kinase deficiency. The Journal of the American Board of Family Practi, [Go to PubMed]
- We report an infant with neonatal hyperbilirubinemia due to pyruvate kinase deficiency. The initial approach involved rapid evaluation, phototherapy, and close monitoring of serum bilirubin levels. Follow-up included maintenance on folic acid, monitoring blood counts, and educating the parents about the course of pyruvate kinase deficiency, especially aplastic crisis. We suggest that the informed family practitioner can manage neonatal hyperbilirubinemia and pyruvate kinase deficiency with referrals at critical times to pediatric or surgical specialists. The practitioner must be able to recognize quickly the need for exchange transfusion for severe jaundice and for blood transfusions or splenectomy when significant anemia or aplastic crisis occurs.