- General Drug Summary
- Drug Name
- Propylthiouracil
- Description
- A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
- Also Known As
- Procasil; Propacil; Propilthiouracil; Propycil; Propyl-Thiorist; Propyl-Thiorit; Propyl-Thyracil; Propylthiorit; Propythiouracil; Prothiucil; Prothiurone; Prothycil; Prothyran; Protiural; Thiuragyl
- Categories
- Antithyroid Agents
- Structure
- Summary In Neonatal Jaundice
-
1 record(s) for Propylthiouracil Adverse Event in Neonatal Jaundice.
- PMID
- Drug Name
- Efficacy
- Evidence
- 580797
- Propylthiouracil
- Adverse Event
- Clinical Trial
- Summary
- Be treated to Graves disease,and may leads to hyperbilirubinemia.
- Diabetes and Graves disease complicating pregnancy. Obstetrics and gynecology, 1978 Jun [Go to PubMed]
- We report here six pregnancies in 5 women with juvenile diabetes and Graves disease. The diabetes was managed in a standard fashion. The Graves disease was managed with propylthiouracil when required. The course of neither the diabetes nor Graves disease was different than expected. When established guidelines for therapy are followed the two have no interaction with one another. One infant was mildly hypothyroid. None developed neonatal Graves disease. Four of the infants had hyperbilirubinemia.