- General Drug Summary
- Description
- The 4-carboxyaldehyde form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. [PubChem]
- Also Known As
- PL; Pyridoxaldehyde; Vitamin B6 hydrochloride
- Categories
- Vitamin B Complex
- Groups
- approved; nutraceutical
- Structure
- Summary In Neonatal Jaundice
-
1 record(s) for Pyridoxal Effective in Maintaining Remission in Neonatal Jaundice.
- PMID
- Drug Name
- Efficacy
- Evidence
- 6741519
- Pyridoxal
- Effective in Maintaining Remission
- Clinical Trial
- Summary
- Pyridoxal is one of the natural forms available of vitamin B6, therefore, it is used for nutritional supplementation and for treating dietary shortage or imbalances.
- Vitamin B6 intake and plasma pyridoxal phosphate concentrations in the first 2 weeks of life. Acta paediatrica Scandinavica, 1984 Mar [Go to PubMed]
- Plasma pyridoxal phosphate concentrations were measured in 178 hospitalised neonates. A reference interval for neonates less than 7 day old, of 25 to 78 nmol/l has been established. Vitamin B6 intakes did not correlate well with plasma pyridoxal concentrations despite 26 neonates receiving less than the Recommended Allowance (0.3 mg/d) and 19 receiving amounts below which convulsions have been associated (0.1 mg/d). Ten percent of those infants fed breast milk had plasma pyridoxal phosphate levels below the reference interval compared with only 4% of those fed milk formulae. Breast milk from mothers with babies less than 14 days old had a total vitamin B6 contents reference interval of 5 to 40 micrograms/l. Twenty percent of breast milk samples had virtually no vitamin B6 detected.