- PMID
- Gene Name
- Molecular Event
- Function in UC
- 1168109
- LPL
- overexpression
- Unclassified
- Method
- NA
- Summary
- lipoprotein lipase activity was increased only in samples provided from mothers whose infants had prolonged Neonatal jaundice.
- [Lipoprotein lipase activity in human milk; inhibition in vitro of the glucuro-conjugation of bilirubin (author's transl)]. Clinica chimica acta; international journal of cli, 1975 Mar 10 [Go to PubMed]
- The lipolytic activities of esterase, lipase and lipoprotein lipase were measured in 17 samples of human milk. Lipase and esterase activities were the same in all samples. However, lipoprotein lipase activity was increased only in samples provided from mothers whose infants had prolonged neonatal jaundice; after storage these samples inhibited the glucuro-conjugation of bilirubin in vitro and their concentration in non-esterified fatty acids was high. The mechanism of action of this enzyme is discussed in relation to the physico-chemical state of fat globules.
- 7408909
- LPL
- overexpression
- Diagnosis
- Method
- NA
- Summary
- These findings indicate that increased values of lipoprotein lipase and free fatty acids in the milk are not responsible for the development of breast-milk jaundice.
- Breast milk jaundice; the role of lipoprotein lipase and the free fatty acids. European journal of pediatrics, 1980 Jun [Go to PubMed]
- Lipoprotein lipase activity and free fatty acid concentrations were measured in samples of milk collected from mothers of infants without and with prolonged neonatal jaundice. The lipoprotein lipase and free fatty acid values in the milk from mothers of infants without jaundice were found to increase with the duration of breast-feeding until the 12th post-partum day, and then to fall to the original levels. In the group of mothers with jaundiced infants both lipoprotein lipase and free fatty acid values were found within normal limits when measured between 15th and 37th days post-partum. These findings indicate that increased values of lipoprotein lipase and free fatty acids in the milk are not responsible for the development of breast-milk jaundice.
2 pubmed articles have reported LPL overexpression associated with Neonatal Jaundice.